Are Granulocyte Transfusions Helpful in Treating and Preventing Infections?
作者： R. G. Strauss
DOI: 10.1007/978-3-642-70385-0_28
关键词:
摘要: “Can granulocyte transfusions (GTX) treatand prevent infections?” Clearly, the answer is “yes”! Should all patients, then, with severe neutropenia (< 500 neutrophils/ μl blood) reeeive therapeutic GTX to treat bacterial infections — or if free of infections, prophylactic infections? Most emphatically, “no”! In this report, literature will be reviewed as it pertains use and supportive care for severely neutropenic patients. Conclusions review are: 1. Therapeutic definitely should used episodes gram-negative septicemia that have failed respond optimal, combination antibiotics. 2. Therapeutic probably shoulde documented fungal other types under similar circumstances. 3. Prophylactic not except in investigational settings. However, renewed considerations might given conducting studies certain clinical
springer.com
springerlink.com参考文章(54)
Ronald G. Strauss, John E. Connett, The Role of Therapeutic and Prophylactic Granulocyte Transfusions in Adult Acute Leukemia Adult Leukemias 1. pp. 351- 380 ,(1982) , 10.1007/978-94-009-7433-3_11
C. D. Buckner, R. A. Clift, E. D. Thomas, J. Hersman, J. E. Sanders, P. S. Stewart, J. C. Wade, M. Murphy, G. Counts, J. D. Meyers, Early infectious complications in allogeneic marrow transplant recipients with acute leukemia: Effects of prophylactic measures Infection. ,vol. 11, pp. 243- 250 ,(1983) , 10.1007/BF01641254
Ronald G. Strauss, Therapeutic neutrophil transfusions The American Journal of Medicine. ,vol. 65, pp. 1001- 1006 ,(1978) , 10.1016/0002-9343(78)90753-2
JP Dutcher, CA Schiffer, GS Johnston, D Papenburg, PA Daly, J Aisner, PH Wiernik, Alloimmunization prevents the migration of transfused indium-111-labeled granulocytes to sites of infection. Blood. ,vol. 62, pp. 354- 360 ,(1983) , 10.1182/BLOOD.V62.2.354.354
J McCullough, BJ Weiblen, ME Clay, L Forstrom, Effect of leukocyte antibodies on the fate in vivo of indium-111-labeled granulocytes. Blood. ,vol. 58, pp. 164- 170 ,(1981) , 10.1182/BLOOD.V58.1.164.164
R. Hasselback, J. E. Curtis, D. E. Bergsagel, Leukocyte transfusions for the prophylaxis and treatment of infections associated with granulocytopenia. Canadian Medical Association Journal. ,vol. 117, pp. 341- 345 ,(1977)
Francesco Laurenti, Rosalia Ferro, Giancarlo Isacchi, Alessandra Panero, Pier Giorgio Savignoni, Franco Malagnino, Palermo Domenico, Franco Mandelli, Giovanni Bucci, Polymorphonuclear leukocyte transfusion for the treatment of sepsis in the newborn infant The Journal of Pediatrics. ,vol. 98, pp. 118- 123 ,(1981) , 10.1016/S0022-3476(81)80556-2
FR Appelbaum, RJ Trapani, RG Graw, Consequences of prior alloimmunization during granulocyte transfusion. Transfusion. ,vol. 17, pp. 460- 464 ,(1977) , 10.1046/J.1537-2995.1977.17578014584.X
D. M. Hahn, S. C, Schimpff, V. M. Young, C. L. Fortner, H. C. Standiford, P. H. Wiernik, Amikacin and Cephalothin: Empiric Regimen for Granulocytopenic Cancer Patients Antimicrobial Agents and Chemotherapy. ,vol. 12, pp. 618- 624 ,(1977) , 10.1128/AAC.12.5.618
Donald J. Higby, Arnold Freeman, Edward S. Henderson, Lucius Sinks, Elias Cohen, Granulocyte transfusions in children using filter-collected cells Cancer. ,vol. 38, pp. 1407- 1413 ,(1976) , 10.1002/1097-0142(197609)38:3<1407::AID-CNCR2820380347>3.0.CO;2-S