Maturation of cellular Fe–S proteins: an essential function of mitochondria

作者: Roland Lill , Gyula Kispal

DOI: 10.1016/S0968-0004(00)01589-9

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摘要: Abstract Iron–sulfur (Fe–S) cluster-containing proteins perform important tasks in catalysis, electron transfer and regulation of gene expression. In eukaryotes, mitochondria are the primary site cluster formation most Fe–S proteins. Assembly clusters is mediated by iron–sulphate assembly (ISC) machinery consisting some ten

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