Therapeutic options in advanced squamous cell lung carcinoma
作者： Hon-Lyn Tan , Yvonne LE Ang , Ross A Soo
DOI: 10.2217/LMT.15.7
关键词:
摘要: SUMMARY The management of advanced-stage NSCLC has been dramatically transformed by the recognition histology-based treatment and use targeted therapy for molecular selected patients with adenocarcinoma. While outcomes have improved adenocarcinoma, options are still limited in squamous cell lung cancer. Through advances characterization cancers, exciting novel targets identified. In this paper, we will review importance histology NSCLC, existing chemotherapy therapies, new subsets inhibitors carcinoma emerging role immune checkpoint inhibitors.
futuremedicine.com 
sci-hub.se 参考文章(91)
Sreenath V. Sharma, Daphne W. Bell, Jeffrey Settleman, Daniel A. Haber, Epidermal growth factor receptor mutations in lung cancer Nature Reviews Cancer. ,vol. 7, pp. 169- 181 ,(2007) , 10.1038/NRC2088
Ross A Soo, Benjamin O Anderson, Byoung Chul Cho, Chih-Hsin Yang, Meilin Liao, Wan-Teck Lim, Peter Goldstraw, Tony S Mok, First-line systemic treatment of advanced stage non-small-cell lung cancer in Asia: consensus statement from the Asian Oncology Summit 2009. Lancet Oncology. ,vol. 10, pp. 1102- 1110 ,(2009) , 10.1016/S1470-2045(09)70238-4
Han Sang Kim, Tetsuya Mitsudomi, Ross A. Soo, Byoung Chul Cho, Personalized therapy on the horizon for squamous cell carcinoma of the lung Lung Cancer. ,vol. 80, pp. 249- 255 ,(2013) , 10.1016/J.LUNGCAN.2013.02.015
S.S. Ramalingam, J. Mazières, D. Planchard, T.E. Stinchcombe, G.K. Dy, S.J. Antonia, L. Horn, H. Lena, E. Minenza, B. Mennecier, G.A. Otterson, L.T. Campos, D.R. Gandara, B.P. Levy, S.G. Nair, G. Zalcman, J. Wolf, C. Baudelet, B.J. Lestini, N.A. Rizvi, Phase II Study of Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in Patients with Advanced, Refractory Squamous Non-Small Cell Lung Cancer International Journal of Radiation Oncology Biology Physics. ,vol. 90, pp. 1266- 1267 ,(2014) , 10.1016/J.IJROBP.2014.09.038
Françoise Dantzer, Valérie Schreiber, Claude Niedergang, Carlotta Trucco, Eric Flatter, Guadalupe De La Rubia, Javier Oliver, Véronique Rolli, Josiane Ménissier-de Murcia, Gilbert de Murcia, Involvement of poly(ADP-ribose) polymerase in base excision repair Biochimie. ,vol. 81, pp. 69- 75 ,(1999) , 10.1016/S0300-9084(99)80040-6
Paolo Ceppi, Marco Volante, Silvia Saviozzi, Ida Rapa, Silvia Novello, Alberto Cambieri, Marco Lo Iacono, Susanna Cappia, Mauro Papotti, Giorgio V. Scagliotti, Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase Cancer. ,vol. 107, pp. 1589- 1596 ,(2006) , 10.1002/CNCR.22208
Nicholas Turner, Richard Grose, Fibroblast growth factor signalling: from development to cancer. Nature Reviews Cancer. ,vol. 10, pp. 116- 129 ,(2010) , 10.1038/NRC2780
Liyun Miao, Yongsheng Wang, Suhua Zhu, Minke Shi, Yan Li, Jingjing Ding, Jun Yang, Qing Ye, Hourong Cai, Deping Zhang, Hongbing Liu, Yong Song, None, Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients BMC Cancer. ,vol. 14, pp. 369- 369 ,(2014) , 10.1186/1471-2407-14-369
Rui Wang, Lei Wang, Yuan Li, Haichuan Hu, Lei Shen, Xuxia Shen, Yunjian Pan, Ting Ye, Yang Zhang, Xiaoyang Luo, Yiliang Zhang, Bin Pan, Bin Li, Hang Li, Jie Zhang, William Pao, Hongbin Ji, Yihua Sun, Haiquan Chen, FGFR1/3 Tyrosine Kinase Fusions Define a Unique Molecular Subtype of Non–Small Cell Lung Cancer Clinical Cancer Research. ,vol. 20, pp. 4107- 4114 ,(2014) , 10.1158/1078-0432.CCR-14-0284
Anna Luisa Di Stefano, Alessandra Fucci, Veronique Frattini, Marianne Labussiere, Karima Mokhtari, Pietro Zoppoli, Yannick Marie, Aurelie Bruno, Blandine Boisselier, Marine Giry, Julien Savatovsky, Mehdi Touat, Hayat Belaid, Aurelie Kamoun, Ahmed Idbaih, Caroline Houillier, Feng R Luo, Jean-Charles Soria, Josep Tabernero, Marica Eoli, Rosina Paterra, Stephen Yip, Kevin Petrecca, Jennifer A Chan, Gaetano Finocchiaro, Anna Lasorella, Marc Sanson, Antonio Iavarone, None, Detection, characterization and inhibition of FGFR-TACC fusions in IDH wild type glioma Clinical Cancer Research. ,vol. 21, pp. 3307- 3317 ,(2015) , 10.1158/1078-0432.CCR-14-2199