Discovery of a novel lead structure for anti-malarials.
作者： Jochen Wiesner , Pia Wißner , Hans-Martin Dahse , Hassan Jomaa , Martin Schlitzer
DOI: 10.1016/S0968-0896(00)00296-0
关键词:
摘要: From a library of 61 compounds available from former studies 2,5-bis-acylaminobenzophenone 7p was identified as lead structure for novel class anti-malaria agents active against multi-resistant Plasmodium falciparum strain Dd2. Some structural modifications this initial demonstrated the potential further improvement anti-plasmodial activity anti-malarials.
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