Photoreactions of phosphorothioate and cysteamine-S-phosphate. Photosubstitution and photophosphoryl transfer.
作者： Hava Neumann , Mordechai Sokolovsky
DOI: 10.1016/0304-4165(75)90235-4
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摘要: Abstract The photoreactions of phosphorothioate and cysteamine- S -phosphate were investigated. On irradiation phosphorothiote a marked change in absorption spectrum was observed. product migrated high voltage electrophoresis, with different mobility from that its dimer, or inorganic orthophosphate. It contained phosphare sulfur ratio 2 : 1, without reducing properties. Therefore it suggested the is either pyrothiophosphate, cyclic compound, similar composition. presence potential phosphoryl group acceptor, such as glucose galactose, 25–40% transferred. formation 6-phosphate, galactose 6-phosphate photolysis gave cysteamine, orthophosphate taurine. Under same conditions irradiation, aminoethanol- O found to be stable.
sci-hub.se 参考文章(21)
Hava Neumann, Robert F. Goldberger, Michael Sela, INTERACTION OF PHOSPHOROTHIOATE WITH THE DISULFIDE BONDS OF RIBONUCLEASE AND LYSOZYME. Journal of Biological Chemistry. ,vol. 239, pp. 1536- 1540 ,(1964) , 10.1016/S0021-9258(18)91348-7
Nathan Sharon, Roger W. Jeanloz, The diaminohexose component of a polysaccharide isolated from Bacillus subtilis. Journal of Biological Chemistry. ,vol. 235, pp. 1- 5 ,(1960) , 10.1016/S0021-9258(18)69572-9
D.A. de Bie, E. Havinga, Photoreactions of aromatic compounds—IV: The directing influence of the methoxy- and the nitro- substituent in the photodeuteration of the benzene nucleus☆ Tetrahedron. ,vol. 21, pp. 2359- 2363 ,(1965) , 10.1016/S0040-4020(01)93890-6
H Neumann, Substrate selectivity in the action of alkaline and acid phosphatases. Journal of Biological Chemistry. ,vol. 243, pp. 4671- 4676 ,(1968) , 10.1016/S0021-9258(18)93171-6
Hava Neumann, Laszlo Boross, Ephraim Katchalski, Hydrolysis of S-Substituted Monoesters of Phosphorothioic Acid by Alkaline Phosphatase from Escherichia coli Journal of Biological Chemistry. ,vol. 242, pp. 3142- 3147 ,(1967) , 10.1016/S0021-9258(18)95944-2
Abraham. Patchornik, Y. Degani, Hava. Neumann, Selective cyanylation of sulfhydryl groups. Journal of the American Chemical Society. ,vol. 92, pp. 6969- 6971 ,(1970) , 10.1021/JA00726A043
E. D. Clercq, F. Eckstein, T. C. Merigan, Interferon Induction Increased through Chemical Modification of a Synthetic Polyribonucleotide Science. ,vol. 165, pp. 1137- 1139 ,(1969) , 10.1126/SCIENCE.165.3898.1137
LÁSZLÓ RÉVÉSZ, HANS MODIG, Cysteamine-induced Increase of Cellular Glutathione-level : A New Hypothesis of the Radioprotective Mechanism Nature. ,vol. 207, pp. 430- 431 ,(1965) , 10.1038/207430A0
Carl J. Scandella, Arthur Kornberg, A membrane-bound phospholipase A1 purified from Escherichia coli. Biochemistry. ,vol. 10, pp. 4447- 4456 ,(1971) , 10.1021/BI00800A015
George L. Ellman, Tissue sulfhydryl groups Archives of Biochemistry and Biophysics. ,vol. 82, pp. 70- 77 ,(1959) , 10.1016/0003-9861(59)90090-6