Trends and patterns of antidepressant use in children and adolescents from five western countries, 2005-2012

摘要: Following the FDA black box warning in 2004, substantial reductions antidepressant (ATD) use were observed within 2 years children and adolescents several countries. However, whether these sustained is not known. The objective of this study was to assess more recent trends ATD youth (0-19 years) for calendar 2005/6-2012 using data extracted from regional or national databases Denmark, Germany, Netherlands, United Kingdom (UK), States (US). In a repeated cross-sectional design, annual prevalence calculated stratified by age, sex, according subclass specific drug. Across years, increased 1.3% 1.6% US (+26.1%); 0.7% 1.1% UK (+54.4%); 0.6% 1.0% Denmark (+60.5%); 0.5% Netherlands (+17.6%); 0.3% Germany (+49.2%). relative growth greatest 15-19 year olds cohorts, 10-14 cohorts. While SSRIs most commonly used ATDs, particularly (81.8% all ATDs), still displayed notable proportions tricyclic (23.0% 19.5%, respectively). Despite sudden decline wake government warnings, trend did persist, contrast, has substantially cohorts five Western