Estrogen receptor signaling as a target for novel breast cancer therapeutics.

作者: Jack-Michel Renoir , Véronique Marsaud , Gwendal Lazennec

DOI: 10.1016/J.BCP.2012.10.018

关键词:

摘要: … In the case of AE or AI resistance, Herceptin or lapatinib may be used to inhibit growth factors. Estrogen effects are mediated not only through nuclear ERs but also through cytoplasmic/…

参考文章(139)
Carine Chavey, Frédéric Bibeau, Sophie Gourgou-Bourgade, Sandrine Burlinchon, Florence Boissière, Daniel Laune, Sylvie Roques, Gwendal Lazennec, None, Oestrogen receptor negative breast cancers exhibit high cytokine content. Breast Cancer Research. ,vol. 9, pp. 1- 11 ,(2007) , 10.1186/BCR1648
Simak Ali, R Charles Coombes, None, Estrogen receptor alpha in human breast cancer: occurrence and significance. Journal of Mammary Gland Biology and Neoplasia. ,vol. 5, pp. 271- 281 ,(2000) , 10.1023/A:1009594727358
J M Renoir, C Radanyi, L E Faber, E E Baulieu, The non-DNA-binding heterooligomeric form of mammalian steroid hormone receptors contains a hsp90-bound 59-kilodalton protein. Journal of Biological Chemistry. ,vol. 265, pp. 10740- 10745 ,(1990) , 10.1016/S0021-9258(18)87009-0
V Duong, A Licznar, R Margueron, N Boulle, M Busson, M Lacroix, B S Katzenellenbogen, V Cavaillès, G Lazennec, ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors. Oncogene. ,vol. 25, pp. 1799- 1806 ,(2006) , 10.1038/SJ.ONC.1209102
Tommaso Simoncini, Ali Hafezi-Moghadam, Derek P. Brazil, Klaus Ley, William W. Chin, James K. Liao, Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase Nature. ,vol. 407, pp. 538- 541 ,(2000) , 10.1038/35035131
Vanesa Lafarga, Ivette Aymerich, Olga Tapia, Federico Mayor, Petronila Penela, A novel GRK2/HDAC6 interaction modulates cell spreading and motility The EMBO Journal. ,vol. 31, pp. 856- 869 ,(2012) , 10.1038/EMBOJ.2011.466
Fei Lan, Xian Feng Wen, Zan Shen, Zhen Zhou Shen, Zhi Ming Shao, The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma. Clinical Cancer Research. ,vol. 8, pp. 2085- 2090 ,(2002)
Muriel Le Romancer, Isabelle Treilleux, Nicolas Leconte, Yannis Robin-Lespinasse, Stéphanie Sentis, Katia Bouchekioua-Bouzaghou, Sophie Goddard, Stéphanie Gobert-Gosse, Laura Corbo, Regulation of Estrogen Rapid Signaling through Arginine Methylation by PRMT1 Molecular Cell. ,vol. 31, pp. 212- 221 ,(2008) , 10.1016/J.MOLCEL.2008.05.025
Lianguo Kang, Xintian Zhang, Yan Xie, Yaping Tu, Dong Wang, Zhenming Liu, Zhao-Yi Wang, Involvement of Estrogen Receptor Variant ER-α36, Not GPR30, in Nongenomic Estrogen Signaling Molecular Endocrinology. ,vol. 24, pp. 709- 721 ,(2010) , 10.1210/ME.2009-0317