Contact sensitization to cyanoacrylate adhesive as a cause of severe onychodystrophy.

摘要: BackgroundThe technology used for artificial nails, the chemistry of cyanoacrylates and reported reactions to these products are briefly reviewed. Materials methodsWe studied three patients with prominent fingernail dystrophy, nail bed hyperkeratosis, fingertip eczema, onycholysis, two whom also had eczematous lesions at distant sites, ostensibly from hand transfer. Patch testing was performed a standard screening tray, dried cyanoacrylate adhesives, and, in one case, clippings. ResultsAll were prominently patch-test positive polymerized 2-ethylcyanoacrylate, as an adhesive on (plastic) fingernails. One patient mildly formaldehyde sensitive, reactive acrylate allergens, extremely allergic toluenesulfonamide resin. patch test her clippings 2 months after use discontinued attempt made remove it. ConclusionsReactions adhesives nails can cause both dystrophy may produce eczema elsewhere, probably Persistence is likely due retained polymer, which slowly degrades presence water releasing antigens. plaster seems be reliable.