Prevalence of microorganisms co-infections in human papillomaviruses infected women in Northern China

摘要: Due to scarce data on the prevalence of genital microorganism infections among individuals with human papillomavirus (HPV) infections, present study aimed evaluate co-infections and associated risk factors in HPV-infected women Northern China. Cervical samples 4290 enrolled female patients were collected detect HPV, bacterial yeast gynecologic outpatients. Serum analyzed for presence serological markers immunodeficiency virus (HIV), hepatitis B (HBV) C (HCV) Treponema pallidum infections. HPV typing was carried out by polymerase chain reaction flow-through hybridization cervical brush specimens. Chlamydia trachomatis identified strand displacement amplification, other microorganisms detected conventional methods. Odds ratio co-infection assessed between HPV-positive -negative patients. Overall, showed a trend compared HPV-negative In this cross-sectional outpatients, statistical analyses revealed significant association detection anti-HBV antibodies, vaginosis, C. Ureaplasma urealyticum; no correlation found infection anti-HIV, anti-HCV, T. pallidum, Trichomonas vaginalis Neisseria gonorrhoeae, which only few cases either or The demonstrated HBV, U. urealyticum. results suggest that it may be important screen simultaneous different have synergistic pathological effects.