Distribution of human papillomavirus in a family planning population in nairobi, kenya.

摘要: Background: In sub-Saharan Africa, cervical cancer is the leading among women. The causative role of different human papillomavirus (HPV) types in established, but distribution HPV within this region largely unknown. Goal: goal was to study family planning clinic attendees Nairobi, Kenya. Study Design: This a cross-sectional persons attending center Results: data 429 women were analyzed; 7.0% had low-grade intraepithelial lesions, 6.8% high-grade and 0.23% invasive cancer. One hundred ninety samples (44.3%) HPV-positive (28.4% positive for multiple types). most common 52 (17.9% samples), 16 (14.7%), 35 (11.6%), 66 (9.0%). risk squamous lesions (HSIL) 88.5 times higher (95% CI, 8.5-1.4 x 10 5 ) 16-positive than HPV-negative Relative risks 54.3 4.0-1.4 35, 49.2 3.6-9.5 4 52, 21.7 0.0-1.9 105) 18. prevalence HSIL not increased association with HIV-positivity, yet HIV-1 significantly associated high-risk (P < 0.00001). Conclusion: pattern population from that other regions world, which has important consequences vaccine development.