Lead-Associated Endocarditis : The Important Role of Methicillin-Resistant Staphylococcus aureus

摘要: Background: Infection is a potentially life-threatening complication of cardiac device implantation. Lead-associated endocarditis (LAE) may be the most serious since it associated with high mortality. Methods: The medical records patients referred to our institution for treatment LAE between 1999 and 2007 were reviewed. Results: A total 51 107 device-related infections met criteria LAE. Of these, 19 occurred within 6 months their recent procedure (early), while remaining 32 more than later (mean = 31.9 post procedure). Devices included pacemakers in 33 ICDs 18 patients. common organism responsible infection was Staphylococcus aureus (S. aureus) followed by coagulase-negative staphylocci (22%) streptococci (12%). Methicillin-resistant S. (MRSA) accounted 67% infections. Coagulase-negative staphylococci only 26% early 19% late cases. distant site (26/51 51%), particularly MRSA leads removed percutaneously all Only one patient failed respond intravenous antibiotics. Conclusions: Our data suggest that methicillin-resistant an important pathogen Since many occur after last procedure, hematogenous spread organisms from contributing factor. These strategies prevent infection, aureus, are critical implantable devices.