Spencer's Pathology of the Lung: The normal lung: histology, embryology, development, aging and function

摘要: Introduction Knowledge of normal lung anatomy and function is important for the interpretation biopsies resections. An understanding different cell structures functions allows a greater appreciation disease states. In addition basic pulmonary embryology explains congenital defects. At other extreme life, knowledge how ages important, not only consideration diseases, such as hiatus hernias with co-existent aspiration, but also because world's increasing elderly population. Development The key events embryogenesis postnatal development are discussed in this chapter. For more detailed account, reader referred to two monographs several review articles. human growth divided into five continuous stages, based on anatomic histological characteristics. These embryonic, pseudoglandular, canalicular, saccular alveolar stages (Table 1) (Figures 1 2). Airway vascular closely related. conducting airways formed embryonic pseudoglandular while gas exchange units characterized by vascularization reduction mesenchyme stages.