A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose
作者： Sarah K. Tate , Rinki Singh , Chin-Chuan Hung , John Jen Tai , Chantal Depondt
DOI: 10.1097/01.FPC.0000230114.41828.73
关键词:
摘要: ObjectivesA broad range of phenytoin doses is used in clinical practice, with the final ‘maintenance’ dose normally determined by trial and error. A common functional polymorphism SCN1A gene (one genes encoding drug target) has been previously associated maximum phenyt
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