A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome

摘要: Abstract Background. The subacute demyelinating polyneuropathy known as Guillain—Barre syndrome improves more rapidly with plasma exchange than supportive care alone. We conducted a multicenter trial to determine whether intravenous immune globulin is effective the complicated treatment exchange. Methods. To enter study, patients had have for less two weeks and be unable walk independently. They were randomly assigned receive either five exchanges (each of 200 250 ml per kilogram body weight) or doses preparation (0.4 g day). predefined outcome measure was improvement at four by least one grade on seven-point scale motor function. Results. After 150 been treated, strength improved in 34 percent those treated exchange, compared 53 (di...