Prevalence of adrenal insufficiency in critically ill patients with AIDS.

作者: Chusana Suankratay , Vichit Prasanthai , Prasit Phowthongkum , Sarat Sunthornyothin

DOI:

关键词:

摘要: Background: The most common endocrine disorder in patients with human immunodeficiency virus (HIV) is adrenocortical dysfunction. prevalence of adrenal insufficiency AIDS is unclear, partly due to different tests, doses adrenocorticotrophic hormone (ACTH), and criteria used. In addition, there is controversy regarding the assessment without critical illness. Objective: To help clarify both and non-critical illness, authors compared based on high-dose ACTH stimulation test. Material Method: There were 26 (19 males 7 females) a mean age 33.6 years (range: 22-46 years). Twelve 14 non-critical respectively. Result: Overall, was 19.2% (5 26) 30.8% (8 when peak stimulated cortisol level < 18 μg/dL 25 defined, 8.3% and 28.6% critically non-critically ill patients; respectively, peak stimulated 18 μg/dL defined. Finally, prevalence was 16.7% 42.9% patients, Conclusion: Adrenal more prevalent than those HIV infection, no matter what response after test are An testing should be performed in all hospitalized AIDS, Keywords: insufficiency, HIV, Critically ill, Adrenocorticotrophic (ACTH) stimulation test

参考文章(23)
Ben J. Glasgow, Kenneth D. Steinsapir, Karl Anders, Lester J. Layfield, Adrenal pathology in the acquired immune deficiency syndrome. American Journal of Clinical Pathology. ,vol. 84, pp. 594- 597 ,(1985) , 10.1093/AJCP/84.5.594
Usha Pulakhandam, Hosoon P. Dincsoy, Cytomegaloviral adrenalitis and adrenal insufficiency in AIDS American Journal of Clinical Pathology. ,vol. 93, pp. 651- 656 ,(1990) , 10.1093/AJCP/93.5.651
Schinella Ra, Niedt Gw, Acquired immunodeficiency syndrome. Clinicopathologic study of 56 autopsies. Archives of Pathology & Laboratory Medicine. ,vol. 109, pp. 727- ,(1985)
Gonzalo Piédrola, Jose L. Casado, Elena López, Ana Moreno, Maria J. Perez-Elías, Rafael García-Robles, Clinical features of adrenal insufficiency in patients with acquired immunodeficiency syndrome Clinical Endocrinology. ,vol. 45, pp. 97- 101 ,(1996) , 10.1111/J.1365-2265.1996.TB02066.X
YOSHIHIKO HOSHINO, NAOHIDE YAMASHITA, TETSUYA NAKAMURA, AIKICHI IWAMOTO, Prospective examination of adrenocortical function in advanced AIDS patients. Endocrine Journal. ,vol. 49, pp. 641- 647 ,(2002) , 10.1507/ENDOCRJ.49.641
Fernando H. Wolff, Claudio Nhuch, Luciana P. Cadore, Cristina L. Glitz, Francisco Lhullier, Tania W. Furlanetto, Low-dose adrenocorticotropin test in patients with the Acquired Immunodeficiency Syndrome Brazilian Journal of Infectious Diseases. ,vol. 5, pp. 53- 59 ,(2001) , 10.1590/S1413-86702001000200002
Mohsen Saleh Eledrisi, Abraham C. Verghese, Adrenal insufficiency in HIV infection: a review and recommendations. The American Journal of the Medical Sciences. ,vol. 321, pp. 137- 144 ,(2001) , 10.1097/00000441-200102000-00005
Paul E. Marik, Kitonga Kiminyo, Gary P. Zaloga, Adrenal insufficiency in critically ill patients with human immunodeficiency virus. Critical Care Medicine. ,vol. 30, pp. 1267- 1273 ,(2002) , 10.1097/00003246-200206000-00018
Jane F. Desforges, Steven K. Grinspoon, John P. Bilezikian, HIV disease and the endocrine system. The New England Journal of Medicine. ,vol. 327, pp. 1360- 1365 ,(1992) , 10.1056/NEJM199211053271906