One-trial context fear conditioning as a function of the interstimulus interval

摘要: In two experiments, we examined the effects of a wide range interstimulus intervals (2.5, 15, 45, 120, 135, and 405 sec) on one-trial context fear conditioning with rats. Here, interval (ISI) denotes time between placement in chamber onset single footshock. On day, observed that rats’ behavior at shock varied systematically across ISI values. subsequent test used context-evoked freezing as measure found well-known inverted U-shaped function. We also conditioned for shortest values was concentrated early session, whereas longer ISIs distributed more evenly throughout session. The results here are consistent literature punctate cues than previously described from fear-conditioning procedures.