作者: M. Saleem Ismail , Pierre N. Tariot
DOI: 10.1007/978-1-59259-661-4_22
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摘要: The cholinergic hypothesis proposes that well-defined deficits in neurotransmission contribute to cognitive dysfunction Alzheimer’s disease (AD), and enhancing transmission will lead improved outcome (1). Several acetylcholinesterase inhibitors (AChEI) have been approved during the past few years on basis of clinical trials, demonstrating these agents improve or maintain function patients with possible AD. Thus far all AChEI shown be efficacious as a class are considered mainstay AD treatment. Galantamine is newest member this at present.