Proteomic profile in Perna viridis after exposed to Prorocentrum lima, a dinoflagellate producing DSP toxins.

摘要: In the current study, we compared protein profiles in gills of Perna viridis after exposure to Prorocentrumlima, a dinoflagellate producing DSP toxins, and identified differential abundances spots using 2D-electrophoresis. After P. lima, level okadaic acid (a main component toxins) significantly increased at 6 h, but mussels were all apparently healthy without death. Among 28 by MALDI TOF/TOF-MS, 12 proteins up-regulated 16 down-regulated lima-exposed mussels. These involved various biological activities, such as metabolism, cytoskeleton, signal transduction, response oxidative stress detoxification. Taken together, our results indicated that presence lima caused toxins accumulation mussel gill, might consequently induce cytoskeletonal disorganization,oxidative stress, dysfunction metabolism ubiquitination/proteasome activity.