A six-year experience with anal cytology in women with HPV in the lower genital tract: utility, limitations, and clinical correlation.

作者: L. H. Cardinal , P. Carballo , M. C. Cabral Lorenzo , A. García , V. Suzuki

DOI: 10.1002/DC.23050

关键词:

摘要: This study assessed the utility and limitations of anal cytology as a screening method for women infected with human papilloma virus (HPV) in lower genital tract. Furthermore, this aimed to establish risk factors pathological cytology/biopsy findings, prevalence anatomopathological lesions associated positive brushings, frequency concomitant tract. A cross-sectional, retrospective, descriptive 207 HPV-associated tract 25 immunosuppression was carried out. Anal cytology, high resolution anoscopy, biopsy suspicious were performed. In total, 232 brushings performed: 184 (79.3%) negative, 24 (10.34%) showed atypical squamous cells undeterminated significance, 18 (7.7%) low-grade intraepithelial lesions, 6 (2.6%) high-grade lesion. Cytohistological correlation obtained 70 cases. The sensitivity detecting 70%, whereas specificity 93%. (84%) higher, than that (66%). most frequently pathology vulvar lesion. It is important perform who have had biopsies due such patients. useful but low. It utmost importance high-resolution anoscopy order confirm pathology. Diagn. Cytopathol. 2014;42:396–400. © 2013 Wiley Periodicals, Inc.

参考文章(16)
William Christopher Mathews, Amy Sitapati, Joseph C. Caperna, R. Edward Barber, Alyssa Tugend, Unyeong Go, Measurement characteristics of anal cytology, histopathology, and high-resolution anoscopic visual impression in an anal dysplasia screening program. Journal of Acquired Immune Deficiency Syndromes. ,vol. 37, pp. 1610- 1615 ,(2004) , 10.1097/00126334-200412150-00014
Shehla Arain, Ann E Walts, Premi Thomas, Shikha Bose, None, The Anal Pap Smear: Cytomorphology of squamous intraepithelial lesions. CytoJournal. ,vol. 2, pp. 4- 4 ,(2005) , 10.1186/1742-6413-2-4
Teresa M. Darragh, Barbara Winkler, Anal cancer and cervical cancer screening: Key differences Cancer Cytopathology. ,vol. 119, pp. 5- 19 ,(2011) , 10.1002/CNCY.20126
R D Cranston, S D Hart, J A Gornbein, S L Hirschowitz, G Cortina, A A Moe, The prevalence, and predictive value, of abnormal anal cytology to diagnose anal dysplasia in a population of HIV-positive men who have sex with men. International Journal of Std & Aids. ,vol. 18, pp. 77- 80 ,(2007) , 10.1258/095646207779949772
J. Michael Berry, Joel M. Palefsky, Naomi Jay, Su-Chun Cheng, Teresa M. Darragh, Peter V. Chin-Hong, Performance characteristics of anal cytology and human papillomavirus testing in patients with high-resolution anoscopy-guided biopsy of high-grade anal intraepithelial neoplasia. Diseases of The Colon & Rectum. ,vol. 52, pp. 239- 247 ,(2009) , 10.1007/DCR.0B013E31819793D9
A.J. Lee, H.T. Papaconstantinou, C.L. Simmang, S.T. Gokasalan, R. Ashfaq, P.J. Huber, S. Sokol, S.G. Gregorcyk, Anal cytology is a poor dysplasia screening test for patients with anal condyloma Journal of Surgical Research. ,vol. 121, pp. 286- ,(2004) , 10.1016/J.JSS.2004.07.066
Gladwyn Leiman, Anal screening cytology. CytoJournal. ,vol. 2, pp. 5- 5 ,(2005) , 10.1186/1742-6413-2-5
O. A. Ogunbiyi, J. H. Scholefield, A. T. Raftery, J. H. F. Smith, S. Duffy, F. Sharp, K. Rogers, Prevalence of anal human papillomavirus infection and intraepithelial neoplasia in renal allograft recipients. British Journal of Surgery. ,vol. 81, pp. 365- 367 ,(2005) , 10.1002/BJS.1800810313
Joel M Palefsky, Elizabeth A Holly, Jimmy T Efirdc, Maria Da Costa, Naomi Jay, J Michael Berry, Teresa M Darragh, Anal intraepithelial neoplasia in the highly active antiretroviral therapy era among HIV-positive men who have sex with men. AIDS. ,vol. 19, pp. 1407- 1414 ,(2005) , 10.1097/01.AIDS.0000181012.62385.4A