作者: Pelagia G. Tsoutsou , Michael I. Koukourakis
DOI: 10.1007/978-1-4020-9819-2_3
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摘要: Angiogenesis consists of the mechanism by which new blood vessels are formed within tumor to sustain its development and growth. This “angiogenic switch” is mediated various molecules deriving from cancer cell and/or tumor-associated stroma promoted either oncogene activation or physiological response any hypoxic stress. The angiogenic switch governed balance between inducers inhibitors.