Angiogenesis and Bone Metastasis: Implications for Diagnosis, Prevention and Treatment

作者: Pelagia G. Tsoutsou , Michael I. Koukourakis

DOI: 10.1007/978-1-4020-9819-2_3

关键词:

摘要: Angiogenesis consists of the mechanism by which new blood vessels are formed within tumor to sustain its development and growth. This “angiogenic switch” is mediated various molecules deriving from cancer cell and/or tumor-associated stroma promoted either oncogene activation or physiological response any hypoxic stress. The angiogenic switch governed balance between inducers inhibitors.

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