Brazilian plants with possible action on the central nervous system: a study of historical sources from the 16th to 19th century

摘要: Brazil is a country rich in biodiversity, endemism, and cultural diversity, inhabited by different types of population. European expeditions the migratory processes that began 16th century greatly contributed both to diversity Brazilian popular therapeutics, produced first records on medicinal plants Brazil. This study comprises bibliographical survey historic books found Sao Paulo libraries (16th through 19th centuries) exerting effects central nervous system (CNS). Thirty-four native were selected from reading books. Of these 34 plants, 13 also recorded ethnopharmacological studies among modern communities 16 have been studied phytochemically. Only eight object pharmacological studies, six these, recently, with request for patent. Results showed most species this reported as centuries, but never investigation down present time. Such results provide ideas selection potentially bioactive be included future studies.