ABO-identical blood group matching has no survival benefit for AB heart transplant recipients.

作者: Henrik Bergenfeldt , Peter Höglund , Bodil Andersson , Göran Rådegran , Mattias Ohlsson

DOI: 10.1016/J.ATHORACSUR.2014.10.031

关键词:

摘要: Background Although identical blood group matching is preferred, it uncertain if this results in improved survival and, so, how large the benefits are. Earlier studies have yielded conflicting and are mostly based on single-center cohorts with few long-term results. Recipients AB of particular interest regarding nonidentical because they may receive organs from all groups. We wanted to test hypothesis that ABO-identical superior recipients AB. Methods used data International Society for Heart Lung Transplantation registry match a cohort heart donors transplant Cox regression analysis was assess influence outcome after transplantation. All-cause cumulative mortality during study period primary end point. Results The material consisted 3,589 adult patients who had received transplants, representing 18,085 patient-years. No significant difference identical, as opposed compatible, ABO found In subgroup analysis, we younger ( p  = 0.02). Conclusions no benefit transplanted organs. than 55 years age, our suggests an organ donor O.

参考文章(25)
Michael Schemper, Terry L. Smith, Efficient evaluation of treatment effects in the presence of missing covariate values. Statistics in Medicine. ,vol. 9, pp. 777- 784 ,(1990) , 10.1002/SIM.4780090707
Ian J. Welsby, Barbara Phillips-Bute, Joseph P. Mathew, Mark F. Newman, Richard Becker, Sunil Rao, Carmelo A. Milano, Mark Stafford-Smith, ABO blood group influences transfusion and survival after cardiac surgery Journal of Thrombosis and Thrombolysis. ,vol. 38, pp. 402- 408 ,(2014) , 10.1007/S11239-013-1045-2
Lars H. Lund, Leah B. Edwards, Anna Y. Kucheryavaya, Anne I. Dipchand, Christian Benden, Jason D. Christie, Fabienne Dobbels, Richard Kirk, Axel O. Rahmel, Roger D. Yusen, Josef Stehlik, The registry of the international society for heart and lung transplantation: Thirtieth official adult heart transplant report - 2013; Focus theme: Age Journal of Heart and Lung Transplantation. ,vol. 32, pp. 951- 964 ,(2013) , 10.1016/J.HEALUN.2013.08.006
A.Michael Borkon, Gregory F Muehlebach, Philip G Jones, Dennis R Bresnahan, Randall E Genton, Michael E Gorton, Nancy D Long, Anthony Magalski, Charles B Porter, William A Reed, Steven K Rowe, An analysis of the effect of age on survival after heart transplant Journal of Heart and Lung Transplantation. ,vol. 18, pp. 668- 674 ,(1999) , 10.1016/S1053-2498(99)00024-8
L. Almenar-Bonet, I.J. Sánchez-Lázaro, L. Martínez-Dolz, Is Age a Limiting Factor for Access to Transplantation? Transplantation Proceedings. ,vol. 43, pp. 2151- 2153 ,(2011) , 10.1016/J.TRANSPROCEED.2011.05.013
Maria Rosa Costanzo, Maria Rosa Costanzo, Anne Dipchand, Randall Starling, Allen Anderson, Michael Chan, Shashank Desai, Savitri Fedson, Patrick Fisher, Gonzalo Gonzales-Stawinski, Luigi Martinelli, David McGiffin, Francesco Parisi, Jon Smith, David Taylor, Bruno Meiser, Steven Webber, David Baran, Michael Carboni, Thomas Dengler, David Feldman, Maria Frigerio, Abdallah Kfoury, Daniel Kim, Jon Kobashigawa, Michael Shullo, Josef Stehlik, Jeffrey Teuteberg, Patricia Uber, Andreas Zuckermann, Sharon Hunt, Michael Burch, Geetha Bhat, Charles Canter, Richard Chinnock, Marisa Crespo-Leiro, Reynolds Delgado, Fabienne Dobbels, Kathleen Grady, Kao W, Jaqueline Lamour, Gareth Parry, Jignesh Patel, Daniela Pini, Sean Pinney, Jeffrey Towbin, Gene Wolfel, Diego Delgado, Howard Eisen, Lee Goldberg, Jeff Hosenpud, Maryl Johnson, Anne Keogh, Clive Lewis, John O'Connell, Joseph Rogers, Heather Ross, Stuart Russell, Johan Vanhaecke, The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients Journal of Heart and Lung Transplantation. ,vol. 29, pp. 914- 956 ,(2010) , 10.1016/J.HEALUN.2010.05.034
Dale G Renlund, David O Taylor, Abdallah G Kfoury, Robert S Shaddy, New UNOS rules: historical background and implications for transplantation management Journal of Heart and Lung Transplantation. ,vol. 18, pp. 1065- 1070 ,(1999) , 10.1016/S1053-2498(99)00075-3
J. O'Donnell, M. A. Laffan, The relationship between ABO histo-blood group, factor VIII and von Willebrand factor. Transfusion Medicine. ,vol. 11, pp. 343- 351 ,(2001) , 10.1046/J.1365-3148.2001.00315.X
Xiaohu Fan, Andrew Ang, Stacey M Pollock-BarZiv, Anne I Dipchand, Phillip Ruiz, Gregory Wilson, Jeffrey L Platt, Lori J West, Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation. Nature Medicine. ,vol. 10, pp. 1227- 1233 ,(2004) , 10.1038/NM1126