Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

作者: Noboru Mizushima , Akiko Kuma , Yoshinori Kobayashi , Akitsugu Yamamoto , Masami Matsubae

DOI: 10.1242/JCS.00381

关键词:

摘要: Macroautophagy is the major intracellular degradation system delivering cytoplasmic components to the lysosome/vacuole. We have shown that, in yeast and mammalian cells, the …

参考文章(30)
Noboru Mizushima, Takeshi Noda, Tamotsu Yoshimori, Yae Tanaka, Tomoko Ishii, Michael D. George, Daniel J. Klionsky, Mariko Ohsumi, Yoshinori Ohsumi, A protein conjugation system essential for autophagy Nature. ,vol. 395, pp. 395- 398 ,(1998) , 10.1038/26506
EFC Blommaart, JJFP Luiken, AJ Meijer, Autophagic proteolysis: Control and specificity Histochemical Journal. ,vol. 29, pp. 365- 385 ,(1997) , 10.1023/A:1026486801018
Yoshinobu Ichimura, Takayoshi Kirisako, Toshifumi Takao, Yoshinori Satomi, Yasutsugu Shimonishi, Naotada Ishihara, Noboru Mizushima, Isei Tanida, Eiki Kominami, Mariko Ohsumi, Takeshi Noda, Yoshinori Ohsumi, A ubiquitin-like system mediates protein lipidation Nature. ,vol. 408, pp. 488- 492 ,(2000) , 10.1038/35044114
Elizabeth A. Craig, Philip James, John Halladay, Genomic Libraries and a Host Strain Designed for Highly Efficient Two-Hybrid Selection in Yeast Genetics. ,vol. 144, pp. 1425- 1436 ,(1996) , 10.1093/GENETICS/144.4.1425
Noboru Mizushima, Hisao Sugita, Tamotsu Yoshimori, Yoshinori Ohsumi, A New Protein Conjugation System in Human: THE COUNTERPART OF THE YEAST Apg12p CONJUGATION SYSTEM ESSENTIAL FOR AUTOPHAGY * Journal of Biological Chemistry. ,vol. 273, pp. 33889- 33892 ,(1998) , 10.1074/JBC.273.51.33889
Ethan Wolf, Peter S. Kim, Bonnie Berger, MultiCoil: A program for predicting two‐and three‐stranded coiled coils Protein Science. ,vol. 6, pp. 1179- 1189 ,(1997) , 10.1002/PRO.5560060606
Tohru Natsume, Yoshio Yamauchi, Hiroshi Nakayama, Takashi Shinkawa, Mitsuaki Yanagida, Nobuhiro Takahashi, Toshiaki Isobe, A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Analytical Chemistry. ,vol. 74, pp. 4725- 4733 ,(2002) , 10.1021/AC020018N
Yukiko Kabeya, Noboru Mizushima, Takashi Ueno, Akitsugu Yamamoto, Takayoshi Kirisako, Takeshi Noda, Eiki Kominami, Yoshinori Ohsumi, Tamotsu Yoshimori, LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing The EMBO Journal. ,vol. 19, pp. 5720- 5728 ,(2000) , 10.1093/EMBOJ/19.21.5720
Kuninori Suzuki, Takayoshi Kirisako, Yoshiaki Kamada, Noboru Mizushima, Takeshi Noda, Yoshinori Ohsumi, The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation The EMBO Journal. ,vol. 20, pp. 5971- 5981 ,(2001) , 10.1093/EMBOJ/20.21.5971
Noboru Mizushima, Yoshinori Ohsumi, Tamotsu Yoshimori, Autophagosome formation in mammalian cells. Cell Structure and Function. ,vol. 27, pp. 421- 429 ,(2002) , 10.1247/CSF.27.421