In Situ Cross-Linkable Hydrogels as a Dynamic Matrix for Tissue Regenerative Medicine
作者： Kyung Min Park , Ki Dong Park
DOI: 10.1007/S13770-018-0155-5
关键词:
摘要: Polymeric hydrogels are extensively used as promising biomaterials in a broad range of biomedical applications, including tissue engineering, regenerative medicine, and drug delivery. These materials have advantages such structural similarity to the native extracellular matrix (ECM), multi-tunable physicochemical biological properties, biocompatibility. In situ forming show phase transition from solution gel state through various physical chemical cross-linking reactions. advanced hydrogel been widely for medicine because ease encapsulating therapeutic agents, cells, drugs, proteins, genes. With advances these utilized either artificial cellular microenvironments create engineered constructs or bioactive acellular matrices stimulate ECM enhanced regeneration restoration. this review, we discuss use cross-linkable engineering applications. particular, focus on emerging technologies powerful tool
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