Effect of 2-Propanol Treatment on Carbon Tetrachloride Metabolism and Toxicity
作者： M. W. Anders , R. N. Harris
DOI: 10.1007/978-1-4757-0674-1_43
关键词:
摘要: The potentiation of carbon tetrachloride (CC14) hepatotoxicity by acute alcohol administration is well known (Cornish and Adefuin, 1967; Strubelt, 1980) although the mechanism this unclear. Carbon must undergo metabolism in order to produce tissue damage (Recknagel Glende, 1973). Several authors have suggested that increased bioactivation involved CC14 (Cote et al., 1974; Maling 1975; Sipes 1973; Strubelt 1978; Traiger Plaa, 1973) but evidence on point largely indirect.
springer.com
sci-hub.st 参考文章(37)
R HARRIS, Effect of fasting, diethyl maleate, and alcohols on carbon tetrachloride-induced hepatotoxicity Toxicology and Applied Pharmacology. ,vol. 56, pp. 191- 198 ,(1980) , 10.1016/0041-008X(80)90289-6
V.L. Kubic, M.W. Anders, Metabolism of carbon tetrachloride to phosgene Life Sciences. ,vol. 26, pp. 2151- 2155 ,(1980) , 10.1016/0024-3205(80)90602-5
Ota Minoru, Sato Nobuko, Uemura Hiroyuki, Obara Kijuro, Lowering effect of carbon tetrachloride on microsomal cytochrome P-450 of rat liver Chemico-Biological Interactions. ,vol. 11, pp. 265- 276 ,(1975) , 10.1016/0009-2797(75)90080-0
George J. Traiger, Gabriel L. Plaa, Effect of Aminotriazole on Isopropanol- and Acetone-Induced Potentiation of CCl4 Hepatotoxicity Canadian Journal of Physiology and Pharmacology. ,vol. 51, pp. 291- 296 ,(1973) , 10.1139/Y73-043
O. Strubelt, Interactions between ethanol and other hepatotoxic agents Biochemical Pharmacology. ,vol. 29, pp. 1445- 1449 ,(1980) , 10.1016/0006-2952(80)90591-2
E.C. de Ferreyra, J.A. Castro, M.I. Díaz Gómez, N. D'Acosta, C.R. de Castro, O.M. de Fenos, Prevention and treatment of carbon tetrachloride hepatotoxicity by cysteine: Studies about its mechanism Toxicology and Applied Pharmacology. ,vol. 27, pp. 558- 568 ,(1974) , 10.1016/0041-008X(74)90035-0
H. Remmer, D. Albrecht, H. Kappus, Lipid peroxidation in isolated hepatocytes from rats ingesting ethanol chronically Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 298, pp. 107- 113 ,(1977) , 10.1007/BF00508617
Michel G. Côte, George J. Traiger, Gabriel L. Plaa, Effect of isopropanol-induced potentiation of carbon tetrachloride on rat hepatic ultrastructure Toxicology and Applied Pharmacology. ,vol. 30, pp. 14- 25 ,(1974) , 10.1016/0041-008X(74)90243-9
O. Strubelt, F. Obermeier, C.P. Siegers, The influence of ethanol pretreatment on the effects of nine hepatotoxic agents. Pharmacology & Toxicology. ,vol. 43, pp. 211- 218 ,(2009) , 10.1111/J.1600-0773.1978.TB02257.X
David Rubinstein, Lewis Kanics, THE CONVERSION OF CARBON TETRACHLORIDE AND CHLOROFORM TO CARBON DIOXIDE BY RAT LIVER HOMOGENATES. Biochemistry and Cell Biology. ,vol. 42, pp. 1577- 1585 ,(1964) , 10.1139/O64-169