摘要: ALLERGEN immunotherapy is the process by which increasing doses of allergen are injected subcutaneously over time as a treatment to prevent allergic symptoms that usually occur on exposure allergen. The effects this therapy immunologic processes ascribed responses have been studied in great detail. EFFECTS OF IMMUNOTHERAPY ON THE INFLAMMATION ASSOCIATED WITH ALLERGIC REACTIONS A number different tools allowed an in-depth look at cellular events, inflammatory responses, and changes diseases. nasal challenge model1has provided means investigating both clinical levels. Typically, standardized inhalation (nasal provocation) induces rhinitis correlate with appearance various mediators (histamine, kinins, prostaglandins, leukotrienes) secretions. Stepwise increases (pollen) dose incremental