Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis.

作者: Stephane Emond , Maya Petek , Emily J. Kay , Brennen Heames , Sean R. A. Devenish

DOI: 10.1038/S41467-020-17061-3

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摘要: … Directed evolution aims at identifying proteins with new functional traits by mimicking the natural process of genetic variation through mutations… the success of directed evolution and the …

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