Estimating the contribution of influenza to hospitalisations in New Zealand from 1994 to 2008.

摘要: Abstract Background Influenza has a substantially but poorly measured impact on population health. Estimating its true contribution to hospitalisations remains challenge. Methods We used simple and comprehensive negative binomial regression models with weekly counts of isolates influenza A, B respiratory syncytial virus for the period 1994– 2008. Results The estimated annual national average number attributable was 822.1(95% CI: 815.3, 828.9) pneumonia influenza, 1861.3 (95% 1842.9, 1879.7) illness, 12.1 2.6, 21.6) circulatory 2260.0 2212.2, 2307.8) all medical illness 2419.9 2356.4, 2483.4) causes. total about nine times larger than indicated by routine discharge data. New Zealanders 80 years age older had highest excess rates influenza-related (327.8 per 100,000); followed infants under 1 year (244.5 100,000). Estimated hospitalisation were also markedly higher in Pacific (83.3 100,000) Māori (80.0 compared European/Others (58.1 Respiratory major contributor cause attributed accounting 77%. included only negligible from illness. Conclusion These findings support efforts reduce particularly most vulnerable groups highlighted here. Analysis cost-effectiveness such interventions needs consider these modelled estimates disease impact.