Effect of single loading dose of intravenous caffeine infusion on superior mesenteric artery blood flow velocities in preterm infants.
作者： Amuchou S Soraisham , Davis Elliott , Harish Amin
DOI: 10.1111/J.1440-1754.2007.01211.X
关键词:
摘要: Aim: To evaluate the effects of a single loading dose caffeine base (10 mg/kg) on superior mesenteric artery (SMA) blood flow velocities (BFV). Methods: Eighteen preterm infants gestational age ≤32 weeks gestation were investigated prospectively. SMA BFV before infusion, 1 h, 2 h and 6 h after measured using Doppler ultrasonography. Results: The peak systolic velocity in decreased by 18% from baseline at 1 h infusion improved towards infusion. reduction was not statistically significant. No significant changes observed heart rate, pressure incidence necrotising enterocolitis. Conclusion: A 10 mg/kg intravenous does cause therefore place intestine increased risk ischemic injury.
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