A randomly branched poly(hydroxyl-β-amino amide): synthesis and complexation
作者： Chuan-bao Wu , Jian-yuan Hao , Xian-mo Deng
DOI: 10.1007/S10965-009-9379-3
关键词:
摘要: A novel type of polycation with high density discrete charge, diversified amino group and abundant hydrophilic short-chains was synthesized from tetraethylenepentamine (TEPA) glycidol acrylate. The obtained abbreviated as PTGA. structure protonation property PTGA characterized by 1H NMR, FTIR, GPC acid-base titration. NMR indicated that there were not only Michael addition ring-opening but also degree amidation during polymerization. Only 12% ester left after So is a kind poly(hydroxyl-β-amino amide). Acid base titration the has wide range shows obvious proton sponge effect. complexation polyanion studied using poly(acrylic acid) (PAA) model polyanion. complex dynamic light scattering UV-Vis spectroscopy. It found size particle first increased then decreased charge ratio to PAA.
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sci-hub.se 参考文章(20)
Kun Luo, Jingbo Yin, Zhijiang Song, Lei Cui, Bin Cao, Xuesi Chen, Biodegradable interpolyelectrolyte complexes based on methoxy poly(ethylene glycol)-b-poly(alpha,L-glutamic acid) and chitosan. Biomacromolecules. ,vol. 9, pp. 2653- 2661 ,(2008) , 10.1021/BM800767F
Nursel Pekel Bayramgil, Thermal degradation of [poly(N-vinylimidazole)–polyacrylic acid] interpolymer complexes Polymer Degradation and Stability. ,vol. 93, pp. 1504- 1509 ,(2008) , 10.1016/J.POLYMDEGRADSTAB.2008.05.006
Lev Bromberg, Svetlana Raduyk, T. Alan Hatton, Angel Concheiro, Cosme Rodriguez-Valencia, Maite Silva, Carmen Alvarez-Lorenzo, Guanidinylated polyethyleneimine-polyoxypropylene-polyoxyethylene conjugates as gene transfection agents. Bioconjugate Chemistry. ,vol. 20, pp. 1044- 1053 ,(2009) , 10.1021/BC900119T
Rima Klimaviciute, Aurimas Riauka, Algirdas Zemaitaitis, The Binding of Anionic Dyes by Cross-Linked Cationic Starches Journal of Polymer Research. ,vol. 14, pp. 67- 73 ,(2007) , 10.1007/S10965-006-9082-6
Meredith A. Mintzer, Eric E. Simanek, Nonviral Vectors for Gene Delivery Chemical Reviews. ,vol. 109, pp. 259- 302 ,(2009) , 10.1021/CR800409E
Daulet E. Zhunuspayev, Grigoriy A. Mun, Patrick Hole, Vitaliy V. Khutoryanskiy, Solvent effects on the formation of nanoparticles and multilayered coatings based on hydrogen-bonded interpolymer complexes of poly(acrylic acid) with homo- and copolymers of N-vinyl pyrrolidone. Langmuir. ,vol. 24, pp. 13742- 13747 ,(2008) , 10.1021/LA802852H
Ken-Yu Chang, Leo-Wang Chen, Tai-Horng Young, Kuo-Huang Hsieh, PEI/EVAL blend membranes for granule neuronal cell culture Journal of Polymer Research. ,vol. 14, pp. 229- 243 ,(2007) , 10.1007/S10965-007-9102-1
Pimwipha Piyakulawat, Nalena Praphairaksit, Nuanphun Chantarasiri, Nongnuj Muangsin, Preparation and evaluation of chitosan/carrageenan beads for controlled release of sodium diclofenac. Aaps Pharmscitech. ,vol. 8, pp. 120- 130 ,(2007) , 10.1208/PT0804097
Mi Ran Park, Ki Ok Han, In Kwon Han, Myung Haing Cho, Jae Woon Nah, Yun Jaie Choi, Chong Su Cho, Degradable polyethylenimine-alt-poly(ethylene glycol) copolymers as novel gene carriers. Journal of Controlled Release. ,vol. 105, pp. 367- 380 ,(2005) , 10.1016/J.JCONREL.2005.04.008
Owen R. Davies, Laura Head, David Armitage, Elizabeth A. Pearson, Martin C. Davies, Maria Marlow, Snjezana Stolnik, Surface modification of microspheres with steric stabilizing and cationic polymers for gene delivery. Langmuir. ,vol. 24, pp. 7138- 7146 ,(2008) , 10.1021/LA703735N