An Analysis of Urinary Prostate Specific Antigen Before and After Radical Prostatectomy: Evidence for Secretion of Prostate Specific Antigen by the Periurethral Glands

作者: James Iwakiri , Kay Grandbois , Nancy Wehner , Howard C.B. Graves , Thomas Stamey

DOI: 10.1016/S0022-5347(17)36207-9

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摘要: AbstractWe investigated whether urinary prostate specific antigen (PSA) might be a useful marker to detect locally recurrent tumor after radical prostatectomy. We also PSA in the first 1 5 cc of voided urine is more indicator levels than midstream PSA, since portion contains highest concentration prostatic and urethral secretions. To determine response prostatectomy, we obtained 18 patients with adenocarcinoma before surgery. Mean decreased from 915.1ng./ml. (range 21 2,853) preoperatively 21.4ng./ml 0.9 88) postoperatively, while mean 245.9ng./ml. 1,312) 1.8ng./ml. 0 20.4) postoperatively.We postoperative 9 cancer p...

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