Permanent Alterations of the L-Forms of Proteus and Salmonella Under Various Conditions

摘要: L-forms obtained from three strains of Proteus and one strain Salmonella have been kept for 15 to 20 years by weekly or monthly transfers on agar plates containing penicillin. The morphology growth requirements these changed. They now grow abundantly the surface in broth. cultures consist large bodies, small granules, transitional forms. These organisms are more resistant distortion stain deeply than usual L-forms. In broth a lesser extent agar, branching filaments develop, ends which both large, round produced. stage development cultures. Usual bacillary forms were not present culture did appear successive absence Bacilli reappeared exposure L influence spore-bearing bacillus. A similar transformation has also observed developing within short time recently isolated B type during process reversion bacterial form. altered fixed transition between L-form regular bacteria.