Amino-Terminal Pro–B-Type Natriuretic Peptide Testing for the Diagnosis or Exclusion of Heart Failure in Patients with Acute Symptoms

摘要: When used for the evaluation of patients with acute symptoms in emergency department setting, amino-terminal pro–B-type natriuretic peptide (NT-proBNP) testing is highly sensitive and specific diagnosis or exclusion destabilized heart failure (HF), results comparable to those reported B-type (BNP) testing. diagnostic patient possible HF, NT-proBNP returns information that may be superior clinical judgment. However, optimal application concert history physical examination, adjunctive testing, knowledge differential an elevated level. Studies indicate a dual use NT-proBNP, both exclude HF (where concentrations 75 years) reduces false-negative findings younger patients, false-positive older improves overall positive predictive value marker without change sensitivity specificity. Clinically validated, cost-effective algorithms exist. Therefore, logical suspected useful, cost-effective, reduce adverse outcomes compared standard