Fast-acting pharmaceutical compositions and methods of use

作者: Douglas William McKay

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摘要: A pharmaceutical composition comprising at least one local anesthetic, anti-inflammatory agent and antibiotic are disclosed. The anesthetic has a peak effect no later than about 10 minutes after administration to mammal, the have half-life of greater 36 hours administration. composition, thus, advantageously provides rapid relief pain with substantially low residual accumulation active components so that can be repeatedly or continuously administered wound. Embodiments include preparing medicinal solution including Lidocaine as Hydrocortisone sodium succinate agent, Chloramphenicol and, optionally, Heparin an anticoagulant. is treat wound mammal maintain constant positive physiological pressure in treated enable permeation fluids from concomitant periodical suctioning debris

参考文章(17)
Elliot B Hagerty, Leon D Freeman, Jess A Bush, Process for preparing crude heparin ,(1957)
Durey H Peterson, Herbert C Murray, Oxygenation of steroids by mucorales fungi ,(1952)
Mildred A Penner, Ehrlich John, Robert M Smith, Process for the manufacture of chloramphenicol ,(1948)
Richard L. Bringham, Scott R. Bell, Blood/gas separator and flow system ,(1990)
Arthur R. Mlodozeniec, John L. Haslam, Takeru Higuchi, Drug delivery system utilizing thermosetting gels ,(1983)
Shuichi Tsuchiya, Tetsuro Kamiya, Kenji Hara, External medication for skin ,(1986)
Thomas A. Fritz, David Yellowhair, VaradaRajan Ramaswami, Guanli Wu, Evan C. Unger, Terry Matsunaga, Therapeutic drug delivery systems ,(1993)