Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose

作者: Herbert Henry Stafford , Hans Lowey

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摘要: A solid pharmaceutical composition in which the carrier consists essentially of hydroxypropylmethylcellulose, or hydroxypropylmethylcellulose admixed with up to about 20% ethylcellulose, is prepared by compressing a mixture comprising one therapeutic agent and powder has been humidified moisture content from 5 25% weight at low compression pressure. The obtained will release active ingredient contained therein evenly over prolonged period, e.g. 1 8 hours.

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