Computation of brain deformations due to violent impact: Quantitative analysis of the importance of the choice of boundary conditions and brain tissue constitutive model

摘要: The objective of this study is to quantify the effects approach for modelling brain-skull interface and constitutive model brain parenchyma on predicting deformations using a previously validated finite element head-brain (Total HUman Model Safety, THUMS, was used). Four approaches two models (linear viscoelastic Odgen hyperviscoelastic) tissue were employed in computer simulations experiments reported literature. Comparison predicted experimentally determined magnitude shape trajectories selected points within as well maximum principal shear strain conducted. comparison indicates that responses strongly affected by both analysed factors. results suggest accurate prediction due violent impact requires allows movement between outer surface skull, while preventing complete separation accounts non-linear stress-strain relationship tissues.