Effect of Bleaching on Mercury Release from Amalgam Fillings and Antioxidant Enzyme Activities: A Pilot Study

作者: Filiz Yalcin Cakir , Esra Ergin , Sevil Gurgan , Suna Sabuncuoglu , Cigdem Sahin Arpa

DOI: 10.1111/JERD.12092

关键词:

摘要: Objective The aim of this pilot clinical study was to determine the mercury release from amalgam fillings and antioxidant enzyme activities (Superoxide Dismutase [SOD] Catalase[CAT] ) in body fluids after exposure two different vital tooth bleaching systems. Material Methods Twenty eight subjects with an average age 25.6 years (18–41) having at least but not more than four Class II on each quadrant arch mouth participated study. Baseline concentrations levels whole blood, urine, saliva were measured by a Vapor Generation Accessory connected Atomic Absorption Spectrometer. Erythrocyte enzymes, SOD, CAT blood determined kinetically. Subjects randomly assigned groups 14 volunteers. Group 1 treated at-home system (Opalescence PF 35% Carbamide Peroxide, Ultradent), 2 chemically activated office Xtra Boost 38% Hydrogen Ultradent) according manufacturer's recommendations. Twenty-four hours treatments, enzymes remeasured. Results  There no significant differences before treatments (p > 0.05). No also found level (SOD CAT) Mercury did affect (p > 0.05). Conclusion  Bleaching either or home amount released antioxidant-enzyme blood. Clinical Significance Bleaching systems tested have deleterious effect fluids.

参考文章(40)
Epperly Ac, Sarrett Dc, Dishman Mv, Robertello Fj, Effect of home bleaching products on mercury release from an admixed amalgam. American Journal of Dentistry. ,vol. 12, pp. 227- ,(1999)
Russell Bogacki, Michael Dishman, Alfred Certosimo, Melanie Wexel, Francis Robertello, The effect of bleaching agents on mercury release from spherical dental amalgam. General dentistry. ,vol. 51, pp. 356- ,(2003)
M.-I. Taticchi, R. Galarini, A.-C. Elia, A.-J.-M. Dörr, L. Mantilacci, Chapter 15 Effects of mercury on glutathione and glutathione-dependent enzymes in catfish (Ictalurus melas R.) Trace Metals in The Environment. ,vol. 4, pp. 411- 421 ,(2000) , 10.1016/S0927-5215(00)80018-1
M Fonzi, A Gasparoni, M Pizzichini, L Fonzi, L Sugherini, A Pompella, M Comporti, Release of mercury from dental amalgam and its influence on salivary antioxidant activity. Bulletin du Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie. ,vol. 42, pp. 94- 100 ,(2000)
M Fonzi, A Gasparoni, M Pizzichini, M Mencarelli, L Fonzi, G Rocchi, V Kaitsas, Influence of amalgam fillings on Hg levels and total antioxidant activity in plasma of healthy donors. Bulletin du Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie. ,vol. 43, pp. 62- 67 ,(2001)
Holger Zimmer, Heidi Ludwig, Michael Bader, Josef Bailer, Peter Eickholz, Hans Jörg Staehle, Gerhard Triebig, Determination of mercury in blood, urine and saliva for the biological monitoring of an exposure from amalgam fillings in a group with self-reported adverse health effects International Journal of Hygiene and Environmental Health. ,vol. 205, pp. 205- 211 ,(2002) , 10.1078/1438-4639-00146
H. Nur Özdabak, Serpil Karaoğlanoğlu, Nilgün Akgül, Fevzi Polat, Nilgün Seven, The effects of amalgam restorations on plasma mercury levels and total antioxidant activity Archives of Oral Biology. ,vol. 53, pp. 1101- 1106 ,(2008) , 10.1016/J.ARCHORALBIO.2008.05.012
S. K. Al-Salehi, Effects of Bleaching on Mercury Ion Release from Dental Amalgam Journal of Dental Research. ,vol. 88, pp. 239- 243 ,(2009) , 10.1177/0022034508328676
Gerhard Gstraunthaler, Walter Pfaller, Peter Kotanko, Glutathione depletion and in vitro lipid peroxidation in mercury or maleate induced acute renal failure Biochemical Pharmacology. ,vol. 32, pp. 2969- 2972 ,(1983) , 10.1016/0006-2952(83)90404-5
Maria Pizzichini, Michele Fonzi, Fabiola Giannerini, Marzia Mencarelli, Alberto Gasparoni, Giovannino Rocchi, Vasilios Kaitsas, Luciano Fonzi, Influence of amalgam fillings on Hg levels and total antioxidant activity in plasma of healthy donors. Science of The Total Environment. ,vol. 301, pp. 43- 50 ,(2003) , 10.1016/S0048-9697(02)00291-7