Gene-Targeting Triple Helix Forming Purine Oligonucleotides
作者： Fedor Svinarchuk , Claude Malvy
DOI: 10.1007/978-1-4615-5177-5_11
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摘要: The recognition of DNA sequences by drags opens up the possibility regulating gene expression at level genes. Natural systems employ large polypeptides to identify sequences. In last 10 years smaller molecules endowed with sequence specificity have been discovered. Among them are PNA Nielsen (1, 2) and cyclic polyamides Dervan (3). As title indicates, we shall devote this review applications cellular a particular class compounds, triple-helix forming purine oligonucleotides. We will not discuss “clamp” approach, where triplex oligonucleotides (TFOs) used inhibit synthesis (4, 5).
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sci-hub.st 参考文章(47)
P A Havre, P M Glazer, Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide. Journal of Virology. ,vol. 67, pp. 7324- 7331 ,(1993) , 10.1128/JVI.67.12.7324-7331.1993
T. Gura, Antisense Has Growing Pains Science. ,vol. 270, pp. 575- 577 ,(1995) , 10.1126/SCIENCE.270.5236.575
Mounira Amor-Gueret, Horea Porumb, Dominique Briane, Valérie Salle, Richard Letellier, Lucien Israël, Hervé Gousset, Jany Vassy, Eliane Taillandier, Temporary ex Vivo Inhibition of the Expression of the Human Oncogene HER2 (NEU) by a Triple Helix-forming Oligonucleotide Cancer Research. ,vol. 56, pp. 515- 522 ,(1996)
Howard B. Gamper,, Igor V. Kutyavin, Rebecca L. Rhinehart, Sergei G. Lokhov, Michael W. Reed, Rich B. Meyer, Modulation of Cm/T, G/A, and G/T triplex stability by conjugate groups in the presence and absence of KCl. Biochemistry. ,vol. 36, pp. 14816- 14826 ,(1997) , 10.1021/BI971339+
Jed N Lampe, Igor V Kutyavin, Rebecca Rhinehart, Michael W Reed, Rich B Meyer, Howard B Gamper, Factors influencing the extent and selectivity of alkylation within triplexes by reactive G/A motif oligonucleotides Nucleic Acids Research. ,vol. 25, pp. 4123- 4131 ,(1997) , 10.1093/NAR/25.20.4123
Luigi E. Xodo, Doroti Pirulli, Franco Quadrifoglio, A Kinetic Study of Triple‐Helix Formation at a Critical R · Y Sequence of the Murine c‐Ki‐ras Promoter by (A,G)‐ and (G,T) Oligonucleotides FEBS Journal. ,vol. 248, pp. 424- 432 ,(1997) , 10.1111/J.1432-1033.1997.00424.X
L. James Maher, Prospects for the Therapeutic Use of Antigene Oligonucleotides Cancer Investigation. ,vol. 14, pp. 66- 82 ,(1996) , 10.3109/07357909609018437
C. Giovannangeli, S. Diviacco, V. Labrousse, S. Gryaznov, P. Charneau, C. Helene, Accessibility of nuclear DNA to triplex-forming oligonucleotides: The integrated HIV-1 provirus as a target Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 79- 84 ,(1997) , 10.1073/PNAS.94.1.79
Sarah B. Noonberg, Jean-Christophe François, Thérsèe Garestier, Claude Héiène, Effect of competing self-structure on triplex formation with purine-rich oligodeoxynucleotides containing GA repeats. Nucleic Acids Research. ,vol. 23, pp. 1956- 1963 ,(1995) , 10.1093/NAR/23.11.1956
J. Cho, M. E. Parks, P. B. Dervan, Cyclic polyamides for recognition in the minor groove of DNA Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 10389- 10392 ,(1995) , 10.1073/PNAS.92.22.10389