Cost-effectiveness of cancer chemotherapy: an economic evaluation of a randomized trial in small-cell lung cancer.

作者: P J Goodwin , R Feld , W K Evans , J Pater

DOI: 10.1200/JCO.1988.6.10.1537

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摘要: An economic evaluation of a randomized trial cyclophosphamide, Adriamycin (doxorubicin; Adria Laboratories, Columbus, OH), and vincristine alone or alternating with etoposide (VP-16) cisplatin in extensive small-cell lung cancer (SCLC) was undertaken. A survival benefit 1.6 months favor chemotherapy associated an additional cost $450 (1984 Canadian dollars) per patient. This translated to $3,370 year life gained. Sensitivity analyses demonstrated that the cost-effectiveness (CEA) greatest when treatment given on outpatient basis. The results were sensitive hospitalization rates, but even most unfavorable revealed CEA be comparable treatments common nonmalignant diseases. It is concluded for SCLC favorable compared accepted be...

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