Chemical components from Gentiana aristata.

作者: Quan-Xiang Wu , Xia Liu , Yan-Ping Shi

DOI: 10.1002/CBDV.200790022

关键词:

摘要: Two new, highly oxygenated ursane-type triterpenoids with an epidioxy function, compounds 1 and 2, as well a new stanside-derived iridoid, compound 10, were isolated from the EtOH extract of Gentiana aristata (whole plant), together 14 known constituents. The structures established on basis detailed spectroscopic investigations, such 1D- 2D-NMR spectroscopy, by means HR-MS. Compounds 3 5-9 screened in vitro for their cytotoxicities against human promyelocytic leukemia (HL-60), ovarian (HO-8910), lung epithelia (A-549) cancer cells.

参考文章(13)
Shan Xie, Shinichi Uesato, Hiroyuki Inouye, Tetsuro Fujita, Fujio Murai, Motoko Tagawa, Tetsuro Shingu, Absolute structure of nepetaside, a new iridoid glucoside from Nepeta cataria Phytochemistry. ,vol. 27, pp. 469- 472 ,(1988) , 10.1016/0031-9422(88)83122-4
Shinichi Uesato, Masami Ueda, Hikoyuki Inouye, Hiroshi Kuwajima, Masaki Yatsuzuka, Kiyokazu Takaishi, Iridoids from Galium mollugo Phytochemistry. ,vol. 23, pp. 2535- 2537 ,(1984) , 10.1016/S0031-9422(00)84093-5
Maryse Hostettmann-Kaldas, Kurt Hostettmann, Otto Sticher, Xanthones, flavones and secoiridoids of american Gentiana species Phytochemistry. ,vol. 20, pp. 443- 446 ,(1981) , 10.1016/S0031-9422(00)84162-X
Salimuzzaman Siddiqui, Farrukh Hafeez, Sabira Begum, Bina S. Siddiqui, Kaneric acid, a new triterpene from the leaves of Nerium oleander Journal of Natural Products. ,vol. 49, pp. 1086- 1090 ,(1986) , 10.1021/NP50048A019
Yoshihiro Mimaki, Masato Fukushima, Akihito Yokosuka, Yutaka Sashida, Shigenori Furuya, Hiroshi Sakagami, Triterpene glycosides from the roots of Sanguisorba officinalis Phytochemistry. ,vol. 57, pp. 773- 779 ,(2001) , 10.1016/S0031-9422(01)00083-8
Regina Bruggisser, Katrin von Daeniken, Gernot Jundt, Willi Schaffner, Heide Tullberg-Reinert, Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay Planta Medica. ,vol. 68, pp. 445- 448 ,(2002) , 10.1055/S-2002-32073
V. S. Prakash Chaturvedula, Zhijie Gao, Shannon H. Jones, Xizhi Feng, Sidney M. Hecht, David G. I. Kingston, A New Ursane Triterpene from Monochaetum vulcanicum that Inhibits DNA Polymerase β Lyase Journal of Natural Products. ,vol. 67, pp. 899- 901 ,(2004) , 10.1021/NP030531B
Hui Min Zhong, Chang Xiang Chen, Xuan Tian, Yu Xin Chui, Yao Zu Chen, Triterpenoid saponins from Clematis tangutica. Planta Medica. ,vol. 67, pp. 484- 488 ,(2001) , 10.1055/S-2001-15803
Zhang Ying-Jun, Yang Chong-Ren, Two triterpenoids from Gentiana tibetica Phytochemistry. ,vol. 36, pp. 997- 999 ,(1994) , 10.1016/S0031-9422(00)90478-3
Q.-X. Wu, Y. Li, Y.-P. Shi, Antioxidant phenolic glucosides from Gentiana piasezkii. Journal of Asian Natural Products Research. ,vol. 8, pp. 391- 396 ,(2006) , 10.1080/10286020500172368