IV Spanish Consensus Conference on Helicobacter pylori infection treatment.

摘要: Helicobacter pylori approximately infect 50% of Spanish population and causes chronic gastritis, peptic ulcer gastric cancer. Until now, three consensus meetings on H.pylori infection had been performed in Spain (the last 2012). The changes the treatment schemes, increasing available evidence, have justified organizing IVSpanish Consensus Conference (March 2016), focused this infection. Nineteen experts participated, who a systematic review scientific evidence developed series recommendation that were subjected to an anonymous Delphi process iterative voting. Scientific strength classified using GRADE guidelines. As starting point, increased minimum acceptable efficacy recommended treatments should reach, or preferably surpass, 90% cure rate when prescribed empirically. Therefore, only quadruple therapies (with without bismuth), generally lasting 14 days, are both for first second line treatments. Non-bismuth concomitant regimen, including proton pump inhibitor, clarithromycin, amoxicillin metronidazole, is as line. In present consensus, other alternatives rescue also reviewed recommended.