Hydrolytic enzyme activities, mainly from lysosomal localization, in sera from patients who ingested a toxic oil

作者: Manuel J. Cabezas-Delamare , Angel Regiero , JoséA. Cabezas

DOI: 10.1016/0009-8981(83)90054-2

关键词:

摘要: Some hydrolytic enzyme activities, mainly typical of lysosomal localization, have been determined in blood sera from patients who ingested a rapeseed oil (denatured with anilines and treated by thermal process), healthy subjects. beta-N-Acetylglucosaminidase, beta-D-glucosidase, beta-D-glucuronidase, alpha-L-fucosidase leucine aminopeptidase activities were significantly higher when compared controls (p less than 0.001); but not significant 0.2) differences found for alpha-D-mannosidase alkaline phosphatase. In contrast, beta-D-galactosidase, alpha-D-galactosidase, acid phosphatase lipase showed lower controls. The significance these results is discussed.

参考文章(17)
Larry D. Strawser, Oscar Touster, The cellular processing of lysosomal enzymes and related proteins. Reviews of Physiology Biochemistry and Pharmacology. ,vol. 87, pp. 169- 210 ,(1980) , 10.1007/BFB0030898
Tanaka Takeo, Kobayashi Masao, Saito Osamu, Kamada Nanao, Kuramoto Atsushi, Usui Tomofusa, Biochemical activities of lysosomal acid hydrolases in leukemic cells Clinica Chimica Acta. ,vol. 117, pp. 121- 131 ,(1981) , 10.1016/0009-8981(81)90033-4
J. Mcmichael, ERUCIC ACID AND THE SPANISH OIL EPIDEMIC The Lancet. ,vol. 318, pp. 1172- 1173 ,(1981) , 10.1016/S0140-6736(81)90622-X
RobertS. Gordon, OLEOANILIDES AND SPANISH OIL POISONING The Lancet. ,vol. 318, pp. 1171- 1172 ,(1981) , 10.1016/S0140-6736(81)90621-8
David Gollob, Round the World The Lancet. ,vol. 318, pp. 1102- ,(1981) , 10.1016/S0140-6736(81)91291-5
JoséM. Miralles, Juan J. Corrales, Luis C. Garcia-Diez, JoséA. Cabezas, Angel Reglero, N-Acetyl β-d-glucosaminidase and α-l-fucosidase activities in relation to glycosylated hemoglobin levels and to retinopathy in diabetes Clinica Chimica Acta. ,vol. 121, pp. 373- 378 ,(1982) , 10.1016/0009-8981(82)90246-7
Angel Reglero, M.Isabel Carretero, JoséA. Cabezas, Increased serum α-l-fucosidase and β-N-acetylglucosaminidase activities in diabetic, cirrhotic and gastric cancer patients Clinica Chimica Acta. ,vol. 103, pp. 155- 158 ,(1980) , 10.1016/0009-8981(80)90207-7