A Community Cluster of Oseltamivir-Resistant Cases of 2009 H1N1 Influenza
作者： Le Quynh Mai , Heiman F.L. Wertheim , Tran Nhu Duong , H. Rogier van Doorn , Nguyen Tran Hien
DOI: 10.1056/NEJMC0910448
关键词:
摘要: To the Editor: Oseltamivir-resistant infection with 2009 pandemic influenza A (H1N1) virus has so far been described only rarely and is conferred by H275Y substitution in neuraminidase enzyme.1 Only 3 of 32 patients oseltamivir-resistant reported on as this writing were not receiving oseltamivir when resistant viruses detected, ongoing community transmission yet shown.1 However, emergence H1N1 remains a grave concern, since widespread resistance observed seasonal H1N1. This was unrelated to selective drug pressure, did . . .
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