Electrospinning of Nanodiamond-Modified Polysaccharide Nanofibers with Physico-Mechanical Properties Close to Natural Skins

摘要: Electrospinning of biopolymers has gained significant interest for the fabrication fibrous mats potential applications in tissue engineering, particularly wound dressing and skin regeneration. In this study, first time, we report successful electrospinning chitosan-based containing bacterial cellulous (33 wt %) medical grade nanodiamonds (MND) (3 nm; up to 3 %). Morphological studies by scanning electron microscopy showed that long uniform fibers with controllable diameters from 80 170 nm were prepared. Introducing diamond nanoparticles facilitated process a decrease size fibers. Fourier transform infrared spectroscopy determined hydrogen bonding between polymeric matrix functional groups MND. It was also found beyond 1 % MND, percolation networks formed which affected properties nanofibrous mats. Uniaxial tensile testing woven enhancement strength (from 13 MPa 25 MP) dispersion The hydrophilicity remarkably improved, favorable cell attachment. water vapor permeability tailorable range 342 423 µg·Pa−1·s−1·m−1. nanodiamond-modified are potentially suitable healing applications.