20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension.
作者： Jan M Williams , Sydney Murphy , Marilyn Burke , Richard J Roman
DOI: 10.1097/FJC.0B013E3181F04B1C
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摘要: Abstract:Arachidonic acid is metabolized by enzymes of the CYP4A and 4F families to 20-hydroxyeicosatetraeonic (20-HETE), which plays an important role in regulation renal function, vascular tone, long-term control arterial pressure. In vasculature, 20-HETE a potent vas
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