作者: Steven L. Young , John Alton Copland
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摘要: The proliferation of uterine fibroid leiomyoma cells is inhibited by certain Fibroid Cell Growth Inhibitor (FGI) agents. pharmacological doses these FGI agents in the milieu can be made high enough to not only inhibit proliferation, but also causes cell death. Non-invasive or minimally invasive, non-systemic delivery methods are used deliver agent target population, thereby avoiding disadvantages and side effects surgical systemic hormonal therapy interventions treatment fibroids. substrates that normally present well tolerated human body. efficacy appears related their ability moderate Protein Kinase C Mitogen Activated pathways. Specific shown useful growth include: α-tocopherol, α-tocopherol succinate, troglitazone. Delivery may accomplished intra-vaginal situ injection techniques already known art.