Intracellular magnesium and magnesium buffering.

摘要: The development of new techniques for measuring intracellular free Mg2+ during the 1980s has provided investigators with tools needed to produce insights into regulation cellular magnesium. Within limits this technology, it appears that all mammalian cells maintain cytosolic levels within fairly narrow range 0.25–1 mM. While transport mechanisms and sequestration organelles will contribute regulation, is binding an as yet poorly defined system buffers largely responsible determining set point regulation. lack adequately Mg2+-selective ionophore remains impediment progress in area.