Photochemistry of the Nucleic Acids

作者: Leonhard Kittler , Günter Löber

DOI: 10.1007/978-1-4684-2577-2_2

关键词:

摘要: Deoxyribonucleic acid (DNA) and ribonucleic (RNA) contain four major bases—adenine, guanine, cytosine, thymine (uracil instead of in RNA)—each which strongly absorbs ultraviolet (UV) radiation with a maximum at about 260 nm. Therefore, UV irradiation nucleic acids related model compounds produces electronically excited bases that are able to undergo various photochemical reactions involving neighboring bases, sugar residues, surrounding water molecules, proteins, bound organic ligands. The properties minor base analogues usually differ from those the normal bases. In view this, study processes may well lead important advances recognition their biochemical functions.

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