Investigational new treatments for Clostridium difficile infection.

摘要: Significant progress has been made by industry and academia in the past two years to address medical threats posed Clostridium difficile infection. These developments provide an excellent example of how patient need driven a surge innovation drug discovery. Indeed, only drugs were approved for infection 30 but there are 13 treatment candidates clinical trials today. What makes latter number even more remarkable is diversity strategies represented (antibiotics, microbiota supplements, vaccines, antibiotic quenchers passive immunization). In this review, we snapshot current stage these breakthroughs argue that still room further treating C.