Multicomponent reactions for the synthesis of multifunctional agents with activity against cancer cells
作者： Saad Shabaan , Lalla A. Ba , Muhammad Abbas , Torsten Burkholz , Annika Denkert
DOI: 10.1039/B823149D
关键词:
摘要: Multicomponent Passerini and Ugi reactions enable the fast efficient synthesis of redox-active multifunctional selenium tellurium compounds, which some show considerable cytotoxicity against specific cancer cells.
rsc.org
sci-hub.se 参考文章(12)
Alex Schneider, Wolfgang Brandt, Ludger A. Wessjohann, Influence of pH and flanking serine on the redox potential of S-S and S-Se bridges of Cys-Cys and Cys-Sec peptides. Biological Chemistry. ,vol. 388, pp. 1099- 1101 ,(2007) , 10.1515/BC.2007.114
Ludger A. Wessjohann, Alex Schneider, Synthesis of Selenocysteine and Its Derivatives with an Emphasis on Selenenylsulfide (SeS) Formation Chemistry & Biodiversity. ,vol. 5, pp. 375- 388 ,(2008) , 10.1002/CBDV.200890038
Franco M. Muggia, Michael D. Green, New anthracycline antitumor antibiotics Critical Reviews in Oncology/Hematology. ,vol. 11, pp. 43- 64 ,(1991) , 10.1016/1040-8428(91)90017-7
Gilson Zeni, Diogo S. Lüdtke, Rodrigo B. Panatieri, Antonio L. Braga, Vinylic tellurides: from preparation to their applicability in organic synthesis. Chemical Reviews. ,vol. 106, pp. 1032- 1076 ,(2006) , 10.1021/CR0505730
Fiona H. FryThese authors contributed equall, Andrea L. Holme, Niroshini M. Giles, Gregory I. Giles, Catriona Collins, Kim Holt, Sandra Pariagh, Thomas Gelbrich, Michael B. Hursthouse, Nick J. Gutowski, Claus Jacob, Multifunctional redox catalysts as selective enhancers of oxidative stress Organic and Biomolecular Chemistry. ,vol. 3, pp. 2579- 2587 ,(2005) , 10.1039/B502197A
Michael C. Pirrung, Koushik Das Sarma, Multicomponent Reactions Are Accelerated in Water Journal of the American Chemical Society. ,vol. 126, pp. 444- 445 ,(2004) , 10.1021/JA038583A
Alexander Dömling, Ivar Ugi, Multicomponent Reactions with Isocyanides. Angewandte Chemie. ,vol. 39, pp. 3168- 3210 ,(2000) , 10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.CO;2-U
Muhammad Abbas, John Bethke, Ludger A. Wessjohann, One pot synthesis of selenocysteine containing peptoid libraries by Ugi multicomponent reactions in water. Chemical Communications. pp. 541- 543 ,(2006) , 10.1039/B514597J
Gregory I. Giles, Niroshini M. Giles, Catriona A. Collins, Kim Holt, Fiona H. Fry, Philip A. S. Lowden, Nicholas J. Gutowski, Claus Jacob, Electrochemical, in vitro and cell culture analysis of integrated redox catalysts: implications for cancer therapy. Chemical Communications. pp. 2030- 2031 ,(2003) , 10.1039/B302877A
I. Ugi, B. Werner, A. Dömling, The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries Molecules. ,vol. 8, pp. 53- 66 ,(2003) , 10.3390/80100053